About Me

After training, research activities and teaching genetics, molecular biology and histology, I was interested in bioinformatics which is now my area of research activity since 2000.

The CBiB (Bordeaux Bioinformatics Center) is one of the scientific and technological platforms of the Bordeaux Functional Genomics Center (CGFB). As an IBiSA-certified platform (www.ibisa.net), the CBiB fulfills research and development, service and training missions in bioinformatics.I am the Assistant Director of the CBiB. I manage bioinformatics projects to meet the needs expressed by biology laboratories.

My work focuses mainly on the analysis of NGS (New Generation of Sequences) data and more particularly on the processing of long reads data: "genome assembly", "diversity of viral species", "clonality of immunoglobulins".

  • Assistant Director of the CBiB
  • Quality Assurance Manager



CESI Aquitaine (Center for Higher Industrial Studies)

Certificate of competence of: «Multimedia Project Manager» (10 months full-time training - 1521 hours)


University of Bordeaux

Doctorate of the University of Bordeaux 2 Life Sciences (Mention Very honorable with the congratulations of the Jury)


University of Bordeaux

DEA Biology-Health option I: gene expression and regulation in eukaryotes (Robert Debré Award 1990 awarded by the High Committee on Alcohol Research and Information)


University of Bordeaux

Master's Degree in Cell Biology, Genetics

University of Bordeaux

License of Biochemistry


Most recent publication (last 3 years)


Nature communications

Following the Adaptive Path of Fruit Tree Domestication using Population Genomics: the Case of Apricots.
Groppi A, Liu S, Cornille A, Decroocq S, Bui QT, Tricon D, Cruaud C, Arribat S, Belser C, Marande W, Salse J, Huneau C, Rodde N, Rhalloussi W, Cauet S, Istace B, Denis E, Carrère S, Audergon JM, Roch G, Lambert P, Zhebentyayeva T, Liu WS, Bouchez O, Lopez-Roques C, Serre RF, Debuchy R, Tran J, Wincker P, Chen X, Pétriacq P, Barre A, Nikolski M, Aury JM, Abbott AG, Giraud T, Decroocq V.
Nat Commun. 2021 Jun 25;12(1):3956



Human Genomics

Novel analytical methods to interpret large sequencing data from small sample sizes.
Lichou F, Orazio S, Dulucq S, Etienne G, Longy M, Hubert C, Groppi A, Monnereau A, Mahon FX and Turcq B.
Hum Genomics. 2019 Aug 30;13(1):41


Life Science Alliance

Small RNA-Seq reveals novel miRNAs shaping the transcriptomic identity of rat brain structures.
Soula A, Valere M, López-González MJ, Ury-Thiery V, Groppi A, Landry M, Nikolski M and Favereaux A.
Life Sci Alliance. 2018 Sep 30;1(5)



AIDS Research and Human Retroviruses

Diversity of HIV-1 in Aquitaine, South-Western France, 2012-2016.
C.Tumiotto, P.Bellecave, P.Recordon-Pinson, A.Groppi, M.Nikolski, and H.Fleury.
AIDS Research and Human Retroviruses Vol. 34, No. 5 2018


Frontiers in Immunology

NGS PacBio full-length sequencing and IMGT/HighV-QUEST analysis of scFv from a phage-display combinatorial library.
A. Hemadou, V. Giudicelli, M. Smith, MP. Lefranc, P. Duroux, S. Kossida C. Heiner, J. Kuijpers, A. Groppi, J. Korlach, P. Mondon, F. Ottones, MJ. Jacobin-Valat, J. Laroche-Traineau and G. Clofent-Sanchez.
Frontiers in Immunology, Frontiers, 2017, 8



Full list of publications : Here



Last Projects

  • All
  • Health
  • Vegetal
  • Other


Centre de Bioinformatique de Bordeaux - CBiB
146, rue Léo Saignat
Case 68
33076 Bordeaux Cedex, France

Phone : +33 6 35 95 04 87

E-mail : alexis.groppi@u-bordeaux.fr